Publications

TGP Students have authored hundreds of publications, many as first authors. This is a small sampling of their accomplishments in the Journals of Cell, Science, & Nature.

Erb, M. A., Scott, T. G., Li, B. E., Xie, H., Paulk, J., Seo, H. S., Souza, A., Roberts, J. M., Dastjerdi, S., Buckley, D. L., Sanjana, N. E., Shalem, O., Nabet, B., Zeid, R., Offei-Addo, N. K., Dhe-Paganon, S., Zhang, F., Orkin, S. H., Winter, G. E., & Bradner, J. E. (2017). Transcription control by the ENL YEATS domain in acute leukaemia. Nature, 543(7644), 270–274. https://doi.org/10.1038/nature21688

Tsherniak, A., Vazquez, F., Montgomery, P. G., Weir, B. A., Kryukov, G., Cowley, G. S., Gill, S., Harrington, W. F., Pantel, S., Krill-Burger, J. M., Meyers, R. M., Ali, L., Goodale, A., Lee, Y., Jiang, G., Hsiao, J., Gerath, W. F. J., Howell, S., Merkel, E., Ghandi, M., … Hahn, W. C. (2017). Defining a Cancer Dependency Map. Cell, 170(3), 564–576.e16. https://doi.org/10.1016/j.cell.2017.06.010

Boulay, G., Sandoval, G. J., Riggi, N., Iyer, S., Buisson, R., Naigles, B., Awad, M. E., Rengarajan, S., Volorio, A., McBride, M. J., Broye, L. C., Zou, L., Stamenkovic, I., Kadoch, C., & Rivera, M. N. (2017). Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. Cell, 171(1), 163–178.e19. https://doi.org/10.1016/j.cell.2017.07.036

Wan, L., Wen, H., Li, Y., Lyu, J., Xi, Y., Hoshii, T., Joseph, J. K., Wang, X., Loh, Y. E., Erb, M. A., Souza, A. L., Bradner, J. E., Shen, L., Li, W., Li, H., Allis, C. D., Armstrong, S. A., & Shi, X. (2017). ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature, 543(7644), 265–269. https://doi.org/10.1038/nature21687

Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L. J., Osborne, B., Joshi, S., Lu, Y., Treviño-Villarreal, J. H., Kang, M. J., Hung, T. T., Lee, B., Williams, E. O., Igarashi, M., Mitchell, J. R., Wu, L. E., Turner, N., Arany, Z., … Sinclair, D. A. (2018). Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. Cell, 173(1), 74–89.e20. https://doi.org/10.1016/j.cell.2018.02.008

Gao, X., Tao, Y., Lamas, V., Huang, M., Yeh, W. H., Pan, B., Hu, Y. J., Hu, J. H., Thompson, D. B., Shu, Y., Li, Y., Wang, H., Yang, S., Xu, Q., Polley, D. B., Liberman, M. C., Kong, W. J., Holt, J. R., Chen, Z. Y., & Liu, D. R. (2018). Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature, 553(7687), 217–221. https://doi.org/10.1038/nature25164

Yan, C., Brunson, D. C., Tang, Q., Do, D., Iftimia, N. A., Moore, J. C., Hayes, M. N., Welker, A. M., Garcia, E. G., Dubash, T. D., Hong, X., Drapkin, B. J., Myers, D. T., Phat, S., Volorio, A., Marvin, D. L., Ligorio, M., Dershowitz, L., McCarthy, K. M., Karabacak, M. N., … Langenau, D. M. (2019). Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish. Cell, 177(7), 1903–1914.e14. https://doi.org/10.1016/j.cell.2019.04.004

Vinogradova, E. V., Zhang, X., Remillard, D., Lazar, D. C., Suciu, R. M., Wang, Y., Bianco, G., Yamashita, Y., Crowley, V. M., Schafroth, M. A., Yokoyama, M., Konrad, D. B., Lum, K. M., Simon, G. M., Kemper, E. K., Lazear, M. R., Yin, S., Blewett, M. M., Dix, M. M., Nguyen, N., … Cravatt, B. F. (2020). An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell, 182(4), 1009–1026.e29. https://doi.org/10.1016/j.cell.2020.07.001

Donovan, K. A., Ferguson, F. M., Bushman, J. W., Eleuteri, N. A., Bhunia, D., Ryu, S., Tan, L., Shi, K., Yue, H., Liu, X., Dobrovolsky, D., Jiang, B., Wang, J., Hao, M., You, I., Teng, M., Liang, Y., Hatcher, J., Li, Z., Manz, T. D., … Fischer, E. S. (2020). Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell, 183(6), 1714–1731.e10. https://doi.org/10.1016/j.cell.2020.10.038

Touat, M., Li, Y. Y., Boynton, A. N., Spurr, L. F., Iorgulescu, J. B., Bohrson, C. L., Cortes-Ciriano, I., Birzu, C., Geduldig, J. E., Pelton, K., Lim-Fat, M. J., Pal, S., Ferrer-Luna, R., Ramkissoon, S. H., Dubois, F., Bellamy, C., Currimjee, N., Bonardi, J., Qian, K., Ho, P., … Ligon, K. L. (2020). Mechanisms and therapeutic implications of hypermutation in gliomas. Nature, 580(7804), 517–523. https://doi.org/10.1038/s41586-020-2209-9

Mercado, N. B., Zahn, R., Wegmann, F., Loos, C., Chandrashekar, A., Yu, J., Liu, J., Peter, L., McMahan, K., Tostanoski, L. H., He, X., Martinez, D. R., Rutten, L., Bos, R., van Manen, D., Vellinga, J., Custers, J., Langedijk, J. P., Kwaks, T., Bakkers, M. J. G., … Barouch, D. H. (2020). Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature, 586(7830), 583–588. https://doi.org/10.1038/s41586-020-2607-z

Lu, Y., Brommer, B., Tian, X., Krishnan, A., Meer, M., Wang, C., Vera, D. L., Zeng, Q., Yu, D., Bonkowski, M. S., Yang, J. H., Zhou, S., Hoffmann, E. M., Karg, M. M., Schultz, M. B., Kane, A. E., Davidsohn, N., Korobkina, E., Chwalek, K., Rajman, L. A., … Sinclair, D. A. (2020). Reprogramming to recover youthful epigenetic information and restore vision. Nature, 588(7836), 124–129. https://doi.org/10.1038/s41586-020-2975-4

Yu, J., Tostanoski, L. H., Peter, L., Mercado, N. B., McMahan, K., Mahrokhian, S. H., Nkolola, J. P., Liu, J., Li, Z., Chandrashekar, A., Martinez, D. R., Loos, C., Atyeo, C., Fischinger, S., Burke, J. S., Slein, M. D., Chen, Y., Zuiani, A., Lelis, F. J. N., Travers, M., … Barouch, D. H. (2020). DNA vaccine protection against SARS-CoV-2 in rhesus macaques. Science (New York, N.Y.), 369(6505), 806–811. https://doi.org/10.1126/science.abc6284

Chandrashekar, A., Liu, J., Martinot, A. J., McMahan, K., Mercado, N. B., Peter, L., Tostanoski, L. H., Yu, J., Maliga, Z., Nekorchuk, M., Busman-Sahay, K., Terry, M., Wrijil, L. M., Ducat, S., Martinez, D. R., Atyeo, C., Fischinger, S., Burke, J. S., Slein, M. D., Pessaint, L., … Barouch, D. H. (2020). SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.), 369(6505), 812–817. https://doi.org/10.1126/science.abc4776

Gebre, M. S., Brito, L. A., Tostanoski, L. H., Edwards, D. K., Carfi, A., & Barouch, D. H. (2021). Novel approaches for vaccine development. Cell, 184(6), 1589–1603. https://doi.org/10.1016/j.cell.2021.02.030

Koikawa, K., Kibe, S., Suizu, F., Sekino, N., Kim, N., Manz, T. D., Pinch, B. J., Akshinthala, D., Verma, A., Gaglia, G., Nezu, Y., Ke, S., Qiu, C., Ohuchida, K., Oda, Y., Lee, T. H., Wegiel, B., Clohessy, J. G., London, N., Santagata, S., … Lu, K. P. (2021). Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. Cell, 184(18), 4753–4771.e27. https://doi.org/10.1016/j.cell.2021.07.020

Ben-Sasson, A. J., Watson, J. L., Sheffler, W., Johnson, M. C., Bittleston, A., Somasundaram, L., Decarreau, J., Jiao, F., Chen, J., Mela, I., Drabek, A. A., Jarrett, S. M., Blacklow, S. C., Kaminski, C. F., Hura, G. L., De Yoreo, J. J., Kollman, J. M., Ruohola-Baker, H., Derivery, E., & Baker, D. (2021). Design of biologically active binary protein 2D materials. Nature, 589(7842), 468–473. https://doi.org/10.1038/s41586-020-03120-8

McMahan, K., Yu, J., Mercado, N. B., Loos, C., Tostanoski, L. H., Chandrashekar, A., Liu, J., Peter, L., Atyeo, C., Zhu, A., Bondzie, E. A., Dagotto, G., Gebre, M. S., Jacob-Dolan, C., Li, Z., Nampanya, F., Patel, S., Pessaint, L., Van Ry, A., Blade, K., … Barouch, D. H. (2021). Correlates of protection against SARS-CoV-2 in rhesus macaques. Nature, 590(7847), 630–634. https://doi.org/10.1038/s41586-020-03041-6

Newby, G. A., Yen, J. S., Woodard, K. J., Mayuranathan, T., Lazzarotto, C. R., Li, Y., Sheppard-Tillman, H., Porter, S. N., Yao, Y., Mayberry, K., Everette, K. A., Jang, Y., Podracky, C. J., Thaman, E., Lechauve, C., Sharma, A., Henderson, J. M., Richter, M. F., Zhao, K. T., Miller, S. M., … Liu, D. R. (2021). Base editing of haematopoietic stem cells rescues sickle cell disease in mice. Nature, 595(7866), 295–302. https://doi.org/10.1038/s41586-021-03609-w

Gebre, M. S., Rauch, S., Roth, N., Yu, J., Chandrashekar, A., Mercado, N. B., He, X., Liu, J., McMahan, K., Martinot, A., Martinez, D. R., Giffin, V., Hope, D., Patel, S., Sellers, D., Sanborn, O., Barrett, J., Liu, X., Cole, A. C., Pessaint, L., … Barouch, D. H. (2022). Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine. Nature, 601(7893), 410–414. https://doi.org/10.1038/s41586-021-04231-6

Larson, R. C., Kann, M. C., Bailey, S. R., Haradhvala, N. J., Llopis, P. M., Bouffard, A. A., Scarfó, I., Leick, M. B., Grauwet, K., Berger, T. R., Stewart, K., Anekal, P. V., Jan, M., Joung, J., Schmidts, A., Ouspenskaia, T., Law, T., Regev, A., Getz, G., & Maus, M. V. (2022). CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours. Nature, 604(7906), 563–570. https://doi.org/10.1038/s41586-022-04585-5

Hauseman, Z. J., Fodor, M., Dhembi, A., Viscomi, J., Egli, D., Bleu, M., Katz, S., Park, E., Jang, D. M., Porter, K. A., Meili, F., Guo, H., Kerr, G., Mollé, S., Velez-Vega, C., Beyer, K. S., Galli, G. G., Maira, S. M., Stams, T., Clark, K., … King, D. A. (2022). Structure of the MRAS-SHOC2-PP1C phosphatase complex. Nature, 609(7926), 416–423. https://doi.org/10.1038/s41586-022-05086-1

Xiao, H., Bozi, L. H. M., Sun, Y., Riley, C. L., Philip, V. M., Chen, M., Li, J., Zhang, T., Mills, E. L., Emont, M. P., Sun, W., Reddy, A., Garrity, R., Long, J., Becher, T., Vitas, L. P., Laznik-Bogoslavski, D., Ordonez, M., Liu, X., Chen, X., … Chouchani, E. T. (2022). Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. Cell, 185(24), 4654–4673.e28. https://doi.org/10.1016/j.cell.2022.10.003

Gungabeesoon, J., Gort-Freitas, N. A., Kiss, M., Bolli, E., Messemaker, M., Siwicki, M., Hicham, M., Bill, R., Koch, P., Cianciaruso, C., Duval, F., Pfirschke, C., Mazzola, M., Peters, S., Homicsko, K., Garris, C., Weissleder, R., Klein, A. M., & Pittet, M. J. (2023). A neutrophil response linked to tumor control in immunotherapy. Cell, 186(7), 1448–1464.e20. https://doi.org/10.1016/j.cell.2023.02.032

McAuley, G. E., Yiu, G., Chang, P. C., Newby, G. A., Campo-Fernandez, B., Fitz-Gibbon, S. T., Wu, X., Kang, S. L., Garibay, A., Butler, J., Christian, V., Wong, R. L., Everette, K. A., Azzun, A., Gelfer, H., Seet, C. S., Narendran, A., Murguia-Favela, L., Romero, Z., Wright, N., … Kohn, D. B. (2023). Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing. Cell, 186(7), 1398–1416.e23. https://doi.org/10.1016/j.cell.2023.02.027

Doman, J. L., Pandey, S., Neugebauer, M. E., An, M., Davis, J. R., Randolph, P. B., McElroy, A., Gao, X. D., Raguram, A., Richter, M. F., Everette, K. A., Banskota, S., Tian, K., Tao, Y. A., Tolar, J., Osborn, M. J., & Liu, D. R. (2023). Phage-assisted evolution and protein engineering yield compact, efficient prime editors. Cell, 186(18), 3983–4002.e26. https://doi.org/10.1016/j.cell.2023.07.039

Mathur, R.,Wang, Q., Schupp, P. G., Nikolic, A., Hilz,S., Hong, C., ... & Costello, J. F. (2024).Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective. Cell,187(2),446-463. https://doi.org/10.1016/j.cell.2023.12.013

Zhao, J., Cato, L. D., Arora, U. P., Bao, E. L., Bryant, S. C., Williams, N., Jia, Y., Goldman, S. R., Nangalia, J., Erb, M. A., Vos, S. M., Armstrong, S. A., & Sankaran, V. G. (2024). Inherited blood cancer predisposition through altered transcription elongation. Cell, 187(3), 642–658.e19. https://doi.org/10.1016/j.cell.2023.12.016